PT 141

🔥 PT-141 (Bremelanotide)

Libido • Neurological Arousal • Sexual Function Research Peptide

Overview:

PT-141, also known as Bremelanotide, is a synthetic peptide originally derived from the melanocortin family (specifically α-MSH analogs). Unlike other agents that act on the vascular system, PT-141 targets the central nervous system to influence sexual desire and arousal pathways directly through melanocortin receptors (MC3R and MC4R) in the brain.

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⚡ Key Research Benefits

    •    Increased Sexual Arousal (CNS-Mediated):

Activates hypothalamic melanocortin receptors associated with libido and arousal, showing both male and female response potential.

    •    Enhanced Dopaminergic Activity:

Research suggests PT-141 modulates dopamine pathways, which play a central role in sexual motivation and mood regulation.

    •    Improved Erectile & Sexual Response:

Demonstrated to improve erectile function and satisfaction in studies independent of nitric-oxide pathways (unlike PDE-5 inhibitors).

    •    Female Sexual Function Studies:

Studied for its role in female sexual interest/arousal disorder (FSIAD), showing significant improvements in desire and responsiveness.

    •    Mood & Confidence Connection:

May positively affect mood and self-perception via central melanocortin activation, contributing to improved quality-of-life metrics in trials.

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🧠 Research Summary

PT-141 represents a neurologically-based approach to sexual function research, focusing on the brain’s signaling of arousal rather than blood flow alone. It has become a primary model compound for studying melanocortin receptor pathways, libido enhancement, and sexual motivation neurochemistry.

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⚠️ Disclaimer

For research purposes only.

Not for human consumption.

All Core Aminos Research compounds are intended exclusively for in-vitro and laboratory investigation.